Future events
Illinois Podiatric Medical Association
2008 Fall Seminar at Holiday Inn Chicago Northshore
Skokie, IL (USA)
November 12, 2008
Join us at the 2008 Fall Seminar IPMA conference in Skokie, IL
at the Holiday Inn Chicago Northshore.
For more information about the conference visit the association website at: http://ipma.net
TCYOD - Taking control of you diabetes
San Diego Convention Center
San Diego, CA (USA)
November 22, 2008
More information about the conference can be found at: http://www.tcoyd.org
Past events
Plastic Surgery 2008
sponsored by
American Society of Plastic Surgeons
Chicago, IL (USA)
October 31-November 5, 2008
We are pleased to announce that Wound-Be-Gone™ will be presented at the Plastic Surgery 2008 in Chicago, IL (October 31 - November 5) sponsored by the American Society of Plastic Surgeons.
Please visit us at our booth - 205 at the McCormick Place West.
For more info about the conference visit www.plasticsurgery.org
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Clinical Symposium on Advances in Skin & Wound Care
The Conference for Prevention and Healing
Las Vegas, NV (USA)
October 26-30, 2008
Join us October 26-30, 2008, at the Rio All Suite Hotel & Casino in Las Vegas, Nevada, for the 23nd Annual Clinical Symposium on Advances in Skin & Wound Care: The Conference for Prevention and Healing. The conference is produced by Wolters Kluwer Health/Lippincott Williams & Wilkins, publisher of Advances in Skin & Wound Care. Visit: http://www.symposiumonwoundcare.com/ for more information.
National Community Pharmacists Association
110th Annual Convention and Trade Exposition
Tampa, FL (USA)
October 11-15, 2008
It was a great show! Thanks to everyone who visited our booth at the NCPA convention. Once again, thank you and we will see you all next year.
http://www.ncpanet.org/
12th Annual Wound Care Congress
Gaylord Palms Resort & Convention Center Florida
Kissimmee, FL (USA)
September 25-29, 2008
This year marks the 12th Annual Wound Care Congress and emphasizes the many dynamic changes taking place in wound care. We look forward to having you join us for 30 hours of the latest issues in wound management presented by our outstanding conference faculty.
Visit http://www.woundcarecongress.com for more info.
The North Central Region (NCR) of the Wound, Ostomy, Continence Nurse’s Society (WOCN)
Radisson Paper Valley Hotel
Appleton, WI (USA)
September 4-6, 2008
For more information about the conference visit http://www.wocn.org
Wound Care SST Conference
Marriott Oak Brook
July 17-19, 2008
Wound-Be-Gone™ will be shown at the Wound Care SST Conference in Oak Brook, IL (USA). Please visit our booth at the front entrance to the exhibit hall in Marriott Oak Brook.
For more information about the conference please visit: www.woundcaresst.com/
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Third Congress of the World Union of Wound Healing Societies
Toronto, Canada
(Toronto, Canada, 4-8 June 2008) - Wake Pharm US, Inc. was one of exhibitors at the 3rd Congress of the World Union of Wound Healing Societies in Toronto, Canada.
From the Would Union of Wound Healing Website:
"One Problem – One Voice!
Treating acute and chronic wounds is an ongoing challenge for health care professionals in all corners of the world. Social, economic, and technological differences, however, can create a vast divide in global approaches to wound care.
However, clinicians are united on one front: prevention and optimal treatment of wounds can be a difficult task.
As a global community of wound care specialists, we need to share our insights, data, and awareness of common wound care concerns and solutions. When we do this, we can build new initiatives to advance wound care practices and to improve patient outcomes globally."
Wound-Be-Gone™ was received as one of the most advanced and innovative products on the market. Experts, scientists, executives and doctors were amazed by the wide range of use of Wound-Be-Gone.
Czech scientists discover new effective substance that speeds up healing processes, even for extensive wounds.
(Prague, 21 November 2007) - Jiří Labský, PhD, one of the project's patent authors together with František Rypáček, PhD., director of the Institute of Macromolecular Chemistry of the Academy of Sciences of the and representatives of Wake Ltd., introduced a new treatment for healing both extensive wounds and skin damage called Wound-Be-Gone*. Wound-Be-Gone* - a polymer carrier combined with another active ingredient - originated in the Czech Republic based on a local patent and is capable of binding free oxygen radicals in a wound. This allows it to markedly expedite healing processes, reduce pain and suppress the development of scabs and scars. Wound-Be-Gone* is effective on what would normally be very difficult to treat skin, i.e. areas afflicted by bed sores or so-called diabetic legs ."Our product is unique in that we were able to integrate into polymer structures an effective trap for free oxygen radicals," explains. Jiří Labský, PhD., one of the two workers at the Institute to whom the patent was awarded. Mr. Labský worked 30 years in the contact lense department, where he ran experiments on integrating traps for free oxygen radicals into polymer structures. In chemical jargon, these traps belong to a group of sterically hindered amines that are used en masse in the rubber industry.
"In one of our research exercises we looked at chemical processes in an eye that was injured by intense UV radiation. At that time we measured, in fact, a very high amount of free oxygen radicals. So we tried to develop a contact lens that would include a trap for these radicals. This lens was able to heal the eye very quickly," continued Mr. Labský.
From there on it was only a small step to using this active ingredient for other types of wounds. Free oxygen radicals develop in large quantities in any spot where the body is injured and infection processes have begun. The substance into which the Institute of Macromolecular Chemistry's team built the sterically hindered amines is called poly(2-hydroxyethyl methacrylate) - the same polymer used to develop soft contact lenses. The discovery of Wound-Be-Gone* thus builds on the work of the Institute's founder, Otto Wichterle, who ran the research institute in the 1960s.
Use of polymer matrices has a number of advantages. They are composed of large macromolecules which are interconnected. This prevents the molecules from penetrating the skin and entering the body. Thus they remain on the wound's surface. This allows the active ingredient to work in a systematic manner. The gel also contains a large amount of water and helps ensure the so-called "moist healing" process in the wound, which also helps in treatments.
In 1997 the invention received a Czech patent, but the process for developing a freely-accessible medication was far from over. Transferring laboratory-proven results into a format that could work in large-scale production was very difficult. Even today production of Wound-Be-Gone* is very complicated and costly.
The patent holder in the EU, the USA, Japan and Canada is the Institute of Macromolecular Chemistry of the Academy of Sciences of the Czech Republic, which, based on a contractual arrangement, provides manufacturing rights to Wake Ltd. "We continue to work on research for using other polymers for healthcare purposes and firmly believe that Wound-Be-Gone* is just the first in a line of many joint projects," added František Rypáček, PhD., director of the Institute of Macromolecular Chemistry.
„The active ingredient in Wound-Be-Gone* was clinically tested in three Czech hospitals. The results show that Wound-Be-Gone* is highly effective in a practical way on all types of wounds and skin damage - from scrapes and cuts to burns and hard-to-heal boils and bed sores," explains Miroslav Vlk, director of Wake Ltd., which manufactures Wound-Be-Gone*. During the tests the company discovered that Wound-Be-Gone* helps in many cases where no one would have expected. "Even though Wound-Be-Gone* is not an antiviral treatment, it helps to heal cold sores. Its impact on healing psoriasis was similarly surprising," continued Mr. Vlk.
Team of Researchers
Jiří Labský, PhD (*1936)
He has written more than 100 articles for international magazines and 55 patent requests. In 2002 he received the prestigious Česká hlava (Czech Brain) award together with Karel Smetana, MD. He contributed to the development of Wound-Be-Gone* with his proposal to incorporate sterically hindered amines, „traps for free oxygen radicals" into certain polymers. He also developed a means for bringing this idea to fruition.
Jiří Vacík, PhD (*1938)
During the 1990s he served as head of the Department of Hydrogels for Medical and Technical Uses at Institute of Macromolecular Chemistry of the Academy of Sciences of the Czech Republic He ran the team developing the Wound-Be-Gone* product. During his 40 plus years working at the Institute for Macromolecular Chemistry he has published 58 expert articles and has authored 47 patent registrations.
Pavel Hošek, MD (*1948)
Worked as a general practitioner. During the research process he focused mainly on the practical testing of the gel.
Profile of Institute of Macromolecular Chemistry of the Academy of Sciences of the Czech Republic
Institute of Macromolecular Chemistry of the Academy of Sciences of the Czech Republic was founded in 1959. Its first director was professor Otto Wichterle, who is known worldwide as the inventor of soft contact lenses and intraocular contact lenses. In recent years the Institute has devoted its work to three key areas: research on biomolecular systems, research on the dynamics and self-organisation of molecular and and supramolecular polymer units and also on the issue of preparation, characterisation and uses for new polymers with manageable structures and features.
Wake Company Profile
Wake Ltd. has developed medications, medical instruments and cosmetic supplies for over a decade. Wake Ltd. works with many important partners in the pharmaceutical sector. These include, for example, Pliva Lachema, ICN Praha, Chemopharma, Promed CS Praha, IV. Pharma, Ltd. (USA and Canada), The Australian Essential Oil Company PTY. Ltd. (Australia), The D.I. Ivanovsky Institute of Virology, the Moscow Clinic for Contagious Diseases No. 1, the Russian Federation's Government Committee for Ecology and other groups. All technological procedures used for manufacturing comply with quality control regulations on environmental protection. Wake Ltd. has system quality management certification for healthcare instruments (ČSN EN ISO 13485:2003) and for environmental management (ČSN EN ISO 14001:2005). Wound-Be-Gone* is the second original medication to be developed by Wake Ltd.
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